EssentHyal™ is a homogeneous injectable hydrogel for medical use. It is indicated for deficit of soft tissues and it allows a long lasting correction and a natural look.


EssentHyal™ is a monophasic hyaluronic acid hydrogel.


EssentHyal™ is suitable for temporary correction of congenital and acquired soft tissue deficits.

Innovative formula

The hyaluronic acid used in our formulation is derived from Bacillus subtilis, a human nonpathogenic microorganism. The result is a high pure product free of contaminant DNA,
proteins and pyrogens, with a decrease of unpredictable adverse reactions.

Long lasting effect

EssentHyal™ is resistant to mechanical stress and it preserves its own mechanical properties, while maintaining an easy handling of injection; so it yields a very good result.


Medical device CE marked, according to DDM 93/42/EEC, manufactured by EUmaterials Srl.

Biological safety and efficacy tests

Both in vitro and in vivo tests, in accordance with the relevant regulations, have demonstrated that EssentHyal™ is highly pure and biocompatible, non-mutagenic, non-toxic, non-sensitizing and resistant to mechanical stresses:

  • Chemical characterization, including FTIR and NMR spectroscopy
  • Mechanical characterization (rheology and texture analysis)
  • In vitro cytotoxicity
  • In vivo implantation test
  • Intracutaneous reactivity test
  • Acute systemic toxicity test
  • Delayed hypersensitivity test
  • Bacterial reverse mutation assay (Ames test)
  • Degradation test

Injection technique

EssentHyal™ can be injected with the techniques commonly used for other hyaluronic acid fillers. It is a mini-invasive procedure and a topical anesthetic administered to the site of injection is enough to avoid the pain.
The augmentation usually lasts five-six months, depending on your life style, body reaction and quantity injected.

Hyaluronic Acid Concentrations and Indications

EssentHyal™26 mg/mlcorrection of medium severity wrinkles, jaw and temple's defects
EssentHyal™ Lip24 mg/mllip's correction
EssentHyal™ PLUS28 mg/mlcorrection of severe nasolabial fold, cheek and chin's defects


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